Substrate: Dual specificity phosphatase 3 (Dual specificity phosphatase)
Seq-ID: P51452 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
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Molecular FunctionCellular ComponentBiological Process
protein tyrosine phosphatase activity,
protein tyrosine/serine/threonine phosphatase activity,
MAP kinase phosphatase activity		 cytosol,
immunological synapse,
nucleoplasm		 negative regulation of T cell activation,
inactivation of MAPK activity,
positive regulation of mitotic cell cycle,
negative regulation of T cell receptor signaling pathway,
peptidyl-tyrosine dephosphorylation,
negative regulation of JNK cascade,
negative regulation of ERK1 and ERK2 cascade
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 138 YSRSPTLVIAYLMMRQKMDVK SYK 12447358
LTP
1.00
 - DSPc
0.17
 1VHR 3.93%
Y 138 YSRSPTLVIAYLMMRQKMDVK ZAP70 12447358
LTP
1.00
 - DSPc
0.17
 1VHR 3.93%

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